Table 1.
Characteristics of the selected proteomics datasets analyzed in this study.
| Number | Publication | Sources | Number of Proteins | Number of AD/CTRL | Age (years) AD/CTRL | Postmortem Interval (h) AD/CTRL |
|---|---|---|---|---|---|---|
| Set-1 | Bai et al. Neuron 202025 | Pooled TMT analysis of Banner Sun cohort | 14513 | 18/18 | 75.7±8.7/83.3±8.0 | 3.3±1.0/2.8±0.6 |
| Set-2 | Bai et al. Neuron 202025 | Individual case TMT analysis of Banner Sun cohort | 12650 | 15/12 | 78.0±8.6/82.9±7.4 | 3.1±0.9/2.6±0.5 |
| Set-3 | Bai et al. Neuron 202025 | Individual case TMT analysis of Mount Sinai cohort | 12147 | 39/23 | 84±10.1/81±10.4 | 6.4±4.4/9.5±6.3 |
| Set-4 | Wang et al. Anal. Chem. 202026 | 16-plex TMT analysis of Banner Sun cohort | 10175 | 8/7 | 57±5.7/57.7 ± 5.2 | 3.0±0.8/NA |
| Set-5 | Higginbotham et al. Sci. Adv. 202027 | Goizueta Alzheimer’s Disease Research Center (ADRC) | 8817 | 10/10 | 65.1±7.4/63.7±10.3 | 5.4±1.5/9.3±7.1 |
| Set-6 | Higginbotham et al. Sci. Adv. 202027 | Goizueta Alzheimer’s Disease Research Center (ADRC) | 11244 | 9/10 | 65.2±7.9/63.7±10.3 | 5.5±1.6/9.3±7.1 |
| Set-7 | Sathe et al. J. Neurochem. 202128 | Baltimore Longitudinal Study of Aging (BLSA) cohort | 8066 | 5/4 | 87 ± 5.7/88 ± 6.8 | NA |