Table 2.
Factors associated with delay in receiving treatment*
| Characteristics | Not treated within 30 days, N = 561 |
Treated within 30 days, N = 501 |
OR1 | 95% CI1 | p-value |
|---|---|---|---|---|---|
| Age at diagnosis, median (IQR) | 68 (62, 78) | 69 (60, 74) | 1.03 | 0.99, 1.06 | 0.12 |
| Gender | |||||
| Female | 24 (43%) | 17 (34%) | — | — | |
| Male | 32 (57%) | 33 (66%) | 0.69 | 0.31, 1.51 | 0.4 |
| WBC at presentation, median (IQR) | 7.9 (6.6, 10.1) | 6.6 (5.2, 8.2) | 1.21 | 1.06, 1.40 | 0.009 |
| Bilirubin level at presentation, median (IQR) | 7 (1, 12) | 2 (1, 9) | 1.04 | 0.99, 1.10 | 0.14 |
| Presented with cholangitis | |||||
| No | 49 (88%) | 49 (98%) | |||
| Yes | 7 (13%) | 1 (2.0%) | |||
| Presented with jaundice | |||||
| No | 24 (43%) | 37 (74%) | — | — | |
| Yes | 32 (57%) | 13 (26%) | 3.79 | 1.69, 8.88 | 0.002 |
| Presented or drained for cholangitis* | 7.26 | 1.87, 48.1 | 0.012 | ||
| 0 | 43 (77%) | 48 (96%) | |||
| 1 | 13 (23%) | 2 (4.0%) | |||
| STENT status | |||||
| No prior STENT | 14 (25%) | 19 (38%) | — | — | |
| Prior STENT/not draining liver | 19 (34%) | 7 (14%) | 3.68 | 1.26, 11.7 | 0.021 |
| Prior STENT/draining liver | 23 (41%) | 24 (48%) | 1.30 | 0.53, 3.22 | 0.6 |
* Treatment was defined as receiving surgery, chemotherapy, radiation, PV embolization within 30 days of presentation
* 1 Univariate logistic regression model estimating the odds ratio of treatment delayed ; OR = Odds ratio CI = confidence interval