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A vertical line at 360 min marks the start of the afternoon (PM) clamp. Glucose infusion rate (A), hepatic glucose uptake (C), non-hepatic glucose uptake (E), and net hepatic carbon retention (G) are shown over time. Their respective areas under the curve (B, D, F, H) are shown for the non-clamp and PM clamp period for Ins4h, Ins2h-A, and Ins2h-B; n=6/group. *P<0.05, **P<0.01 between groups. ns = not significant.
