FIG. 1.

Mean levels of IFN-γ (A) and IL-2 (B) released from bovine PPD-stimulated whole-blood cultures and serum antibody responses to M. bovis culture filtrate (C) for animals vaccinated with CFP (▴) (n = 10), BCG (▪) (n = 10), or CFP and BCG (×) (n = 9) and for nonvaccinated animals (⋄) (n = 10). IFN-γ levels are presented as mean concentrations in plasma (ng/ml), IL-2 levels are given as mean stimulation indexes (SI), and antibody levels are given as percentages of a positive control serum. The bars above the data points represent SEM. The arrows indicate vaccination times (0 for BCG and 0, 3, and 6 weeks for CFP).