TABLE 1.

Survival of internalized N. meningitidis after antibiotic treatment in cultures incubated without L-NMMA^a

Parameter	No. of CFU after incubation for:
	30 min			60 min			90 min			120 min
	Wild type	norB	cycP	Wild type	norB	cycP	Wild type	norB	cycP	Wild type	norB	cycP
	16.50	8.40	11.50	53.90	17.10		920.00		500.00	3.70	1.10	1.50
	22.80		2.70	6.85	13.20	5.00	11420.00	9415.00	11170.00	30.35	7.70	1.20
	12.60	6.00	0					34.00	50.00	8.55	7.70	5.50
	17.10	0.00	1.15		0	1.30	7.00	0	0	0	0	0.05
		8.70	4.00	0.10	0.20	0.90	240.00	5.00	0		0.60
		26.70	198.40	250.00		120.00	695.00	260.00	600.00
	5.20	3.90	2.75		86.00	27.80	775.00	145.00		1.50		0.70
	6.35	9.20	1.65	264.00	180.00	10.60	1245.00	65.00	245.00	2.50	0.10	1.30
	2.70	0.60	1.65	3.40	1.30	3.00	201.00	5.00		0.30	0.05	0.00
	1.20	0.05	1.40	5.10	0.20	0.60				2.30	1.40	1.90
	2.85	0.70	0.25	8.60	2.90	16.50				2.90	0.30
	118.33	1.10	28.30	3.35	5.85	8.33
	167.80	133.33	120.00	262.23	98.87	146.40
	1.00	18.50	1.67	3.50	26.75	79.82				0.42	0.17	0.09
	0.13	0	0.27	0.77	0.13	0
	12.25	0.05	1.20	6.80	1.05	2.85				3.40	0	0.05
	19.35	0.45	0.10	9.35	0.95	6.80				5.50	0.85
	162.70	92.75	93.65	15.00	30.40	13.00				10.20	0.50	11.35
	350.00	3.80	10.20	21.35	2.00	14.20				5.95	0.05	1.95
	3.70	0.04	3.37	8.91	1.11	1.67				0.63	0.46	1.39
	343.33	722.50	452.50	1560.00	720.83	533.33
	63.80	3.85	8.00	22.55	1.40	2.45
	35.55	5.20	4.50	70.70	3.85	3.85
Median value	16.5	3.88	2.75	9.13	2.9	6.8	735	49.5	245	2.9	0.46	1.3
25th percentile	3.28	0.35	1.2	3.9	1	2.06	210.75	5	0	0.63	0.05	0.07
75th percentile	91.07	11.53	11.5	66.5	28.58	22.15	1163.75	231.25	600	5.95	1.1	1.93

^aComparison of data by Wilcoxon signed rank test analysis of statistically significant differences gave the following P values (with incubation times in parentheses): for wild type versus norB, P = 0.012 (30 min), 0.022 (60 min), 0.018 (90 min), and 0.01 (120 min); for wild type versus cycP, P = 0.02 (30 min), 0.024 (60 min), 0.028 (90 min), and 0.023 (120 min).