Figure 4.

Immunohistochemistry of microglial cells labeled by Iba-1 in the cortex, Cpu, and hilus: (A) representative photomicrographs; (B–D) summarized mean Iba-1-positive staining intensity. LPS significantly increased the number of microglial cells after 24 h in the cortex and Cpu, while B355252 successfully decreased the numbers of Iba-1-labeled microglial cells in the cortex and Cpu. Data in bar graphs are presented as mean +/− SD. Significance levels are denoted as *, ** for p < 0.05, 0.01 vs. NC (naïve control); ## for p < 0.01 vs. LPS24h. The scale bar represents 100 µm.