Table 1.
2023 FIGO staging of endometrial cancer [4].
| Stages | Description |
|---|---|
| Stage I | Confined to uterine corpus and ovary a |
| IA | Disease limited to the endometrium OR non-aggressive histological type, with < 50% myometrial involvement, no focal LVSI b, or good disease prognosis. |
| IA1 | Non-aggressive histological type limited to an endometrial polyp or confined to endometrium. |
| IA2 | Non-aggressive histological type with < 50% myometrial involvement with no to focal LVSI b. |
| IA3 | Low-grade endometrioid carcinomas limited to uterus or ovary a. |
| IB | Non-aggressive histological type with > 50% myometrial invasion, and no to focal LVSI b. |
| IC | Aggressive histological subtype limited to a polyp or confined to endometrium. |
| Stage II | Invasion of cervical stroma with no extrauterine extension, or substantial LVSI b, or aggressive histological type with any myometrial invasion. |
| IIA | Non-aggressive histological type with invasion of cervical stroma. |
| IIB | Non-aggressive histological type with substantial LVSI b. |
| IIC | Aggressive histological subtype with any myometrial involvement. |
| Stage III | Local and/or regional metastasis of any histological subtype. |
| IIIA | Invasion of uterine serosa, adnexa, or both. |
| IIIA1 | Spread to ovary or fallopian tube (excluding lesions that meet stage IA3 criteria a). |
| IIIA2 | Spread to uterine subserosa or through uterine serosa. |
| IIIB | Metastasis or direct spread to the vaginal canal and/or parametria or pelvic peritoneum. |
| IIIB1 | Metastasis or direct spread to the vaginal canal and/or parametria. |
| IIIB2 | Metastasis to pelvic peritoneum. |
| IIIC | Metastasis to pelvic and/or para-aortic lymph nodes. |
| IIIC1 | Metastasis to pelvic lymph nodes. |
| IIIC1i | Micrometastasis to pelvic lymph nodes. |
| IIIC1ii | Macrometastasis to pelvic lymph nodes. |
| IIIC2 | Metastasis to para-aortic lymph nodes up to the renal vessels, and/or pelvic lymph node metastasis. |
| IIIC2i | Micrometastasis to para-aortic lymph nodes up to the renal vessels, and/or pelvic lymph node metastasis. |
| IIIC2ii | Macrometastasis to para-aortic lymph nodes up to the renal vessels, and/or pelvic lymph node metastasis. |
| Stage IV | Spread to the bladder mucosa and/or intestinal mucosa and/or distant metastasis. |
| IVA | Spread to the bladder mucosa and/or intestinal mucosa. |
| IVB | Abdominal peritoneal metastasis beyond the pelvic peritoneum, |
| IVC | Distant metastasis, included metastasis to any extra-abdominal or intra-abdominal lymph nodes superior to the renal vessels, lungs, liver, brain, or bone. |
a Concurrent uterine and ovarian low-grade endometrioid endometrial carcinoma are included in this stage if the following criteria are met: (1) No more than 50% of myometrial involvement, (2) absence of extensive LVSI, (3) absence of additional metastasis, and (4) unilateral ovarian involvement without capsule rupture or invasion. b Lymphovascular invasion.