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. 2024 Jan 29;14(5):2137–2152. doi: 10.1016/j.apsb.2024.01.014

Figure 6.

Figure 6

ERβ agonist conjugates enhance skin conditions. (A, B) Aged mouse skin slices were immunostained for Ki67 and p63 with quantification, under vehicle or VB-165 treatment. Scale bar, 10 μm. ∗P < 0.05, n = 5. (C) H&E staining of the skin in aged mice after VB-165 treatment. Scale bar, 10 μm. (D, E) Immunostaining of excision skin slices for Ki67 and p63, with quantification under vehicle or JW-191 treatment. Scale bars, 10 μm. ∗P < 0.05, ∗∗P < 0.01, n = 4. (F) H&E staining of excision skin between vehicle and JW-191 treatment groups. Scale bar, 10 μm. All values are presented as the mean ± SEM.