TABLE 3.
The 25 most highly induced genes in the wild-type strain as determined by microarray analysis, sorted by induction ratio
| Locus | Gene name | Induction ratio R1a | Predicted functionb |
|---|---|---|---|
| DR1114 | hsp20 | 11.99 | Small heat shock protein |
| DR0127 | 11.06 | Hypothetical | |
| DR0128 | grpE | 10.77 | Chaperone |
| DR1046 | clpB | 8.02 | ATP-dependent Clp protease |
| DRA0199 | 7.95 | Nodulation protein N-related protein | |
| DR0126 | dnaJ | 7.90 | Chaperone |
| DR0129 | dnaK | 7.49 | Chaperone |
| DR2381 | 7.35 | Aldehyde dehydrogenase | |
| DR0561 | 6.07 | Maltose ABC transporter, periplasmic maltose-binding protein | |
| DR0178 | 5.91 | Transposase, putative | |
| DR0349 | lon | 5.80 | ATP-dependent protease |
| DR0997 | 5.41 | Transcriptional regulator, FNR/CRP family | |
| DR1082 | lrpA | 5.30 | Light-repressed protein A, putative |
| DR1019 | 4.99 | Glycerol-3-phosphate dehydrogenase | |
| DR0220 | 4.83 | Amidophosphoribosyltransferase | |
| DR2307 | 4.76 | Multidrug efflux transporter, putative | |
| DR2386 | paaA | 4.70 | Phenylacetic acid degradation protein |
| DRA0200 | 4.62 | Oxidoreductase, short-chain dehydrogenase/reductase family | |
| DR1473 | pspA | 4.50 | Phage shock related protein |
| DRC0007 | 4.38 | Hypothetical protein | |
| DRB0012 | 4.35 | Cobyric acid synthase | |
| DR1314 | 4.35 | Conserved hypothetical protein | |
| DR0392 | 4.34 | Hypothetical protein | |
| DRB0083 | 4.32 | Potassium-transporting ATPase, B subunit | |
| DR0194 | 4.27 | Conserved hypothetical protein |
a
Numbers represent average ratios of 48°C and 30°C intensity values from five replicate data sets.
b
Functional annotations are taken from the D. radiodurans completed genome sequence (45; www.tigr.org).