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. 2024 May 10;13(10):816. doi: 10.3390/cells13100816

Figure 6.

Figure 6

CTTN is a functional and major target of UCHL1 in NPC. (A,B) Transwell assay performed with SUNE1 (A) or HONE1 (B) cells stably transfected with control or shUCHL1 and reconstructed with vector, UCHL1, or UCHL1(C90S) in the presence (invasion) or absence (migration) of Matrigel. (C,D) Transwell assay performed with SUNE1 (C) or HONE1 (D) cells that stably transfected with vector or UCHL1 with reconstructed with vector or CTTN in the presence (invasion) or absence (migration) of Matrigel. Scale bar: 100 µm; Mean ± S.D.; * p < 0.05, ** p < 0.01, *** p < 0.001, NS: no significance compared with vector; Student’s t-tests. Data are representative of at least three independent experiments.