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Measured concentrations (LC-MS/MS) of drugs in the tumor (median with 5–95% confidence interval).
| Male (N = 4) | BI-3406 (µM) | Trametinib (µM) | BKM120 (µM) |
|---|---|---|---|
| Median (5–95% CI) | 2.4 (0.12–9.3) | 0.21 (0.02–0.65) | 2.1 (0.68–3.6) |
| Female (N = 6) | BI-3406 (µM) | Trametinib (µM) | BKM120 (µM) |
| Median (5–95% CI) | 3.8 (0.16–38) | 0.16 (0.01–1.4) | 2.4 (0.41–24) |
