FIG. 1.

Deduced amino acid sequences of 10 serotypes of staphylocoagulase compared using the CLUSTAL X program. The corresponding nucleotide sequences were determined using DNA fragments of the following strains: 104 (type I coa), N315 (type II), NCTC 8325 (type III), Stp-28 (type IV), no. 55 (type V), Stp-12 (type VI), MW2 (type VII), Ku (type VIII), 17573 (type IX), and 19 (type X). The highly conserved residues among 10 staphylocoagulases are shown in gray to highlight them. The identical or conserved residues are marked with an asterisk, colon, or period at the top. The residues which are in contact with the 148 loop or exosite I reported by Friedrich et al. (12) are indicated as closed or open triangles, respectively. PA, prothrombin-activated domain; CT, C-terminal sequence.