Table 3.

Genotype frequencies of ABCB1 polymorphisms under investigation and outcomes.

		Relapsed							Resistant (TRD)
		No		Yes		OR	CI 95%	p-Value	No		Yes		OR	CI 95%	p-Value
		N	%	N	%				N	%	N	%
C1236T (rs1128503)	CC	18	40.0	7	43.8	1.0	Referent	-	25	41.0	7	36.8	1.0	Referent	-
	CT	22	48.9	6	37.5	0.701	[0.200–2.462]	0.579	28	45.9	9	47.4	1.148	[0.373–3.537]	0.810
	TT	5	11.1	3	18.7	1.543	[0.288–8.250]	0.673 *	8	13.1	3	15.8	1.339	[0.279–6.434]	0.698 *
	T carrier	27	60.0	9	56.3	0.857	[0.270–2.717]	0.793	36	59.0	12	63.2	1.190	[0.411–3.445]	0.748
C3435T (rs1045642)	CC	13	29.5	5	33.3	1.0	Referent	-	18	30.5	5	27.8	1.0	Referent	-
	CT	24	54.6	6	40.0	0.650	[0.166–2.546]	0.535	30	50.9	9	50.0	1.080	[0.313–3.731]	0.903
	TT	7	15.9	4	26.7	1.486	[0.299–7.389]	0.694 *	11	18.6	4	22.2	1.309	[0.288–5.948]	1.000 *
	T carrier	31	70.5	10	66.7	0.839	[0.239–2.938]	0.783	41	69.5	13	72.2	1.141	[0.354–3.681]	0.825
G2677TA (rs2032582)	GG	19	42.2	7	43.8	1.0	Referent	-	26	42.6	6	31.6	1.0	Referent	-
	GT	18	40.0	7	43.8	1.056	[0.308–3.612]	0.931	25	41.0	11	57.9	1.907	[0.612–5.939]	0.262
	GA	1	2.2	0	0	**	**	1.000 *	1	1.6	0	0.0	**	**	1.000 *
	TT	4	8.9	2	12.5	1.357	[0.202–9.126]	1.000 *	6	9.8	2	10.5	1.444	[0.232–9.005]	0.650 *
	AA	0	0.0	0	0.0	-	-	-	0	0.0	0	0.0	-	-	-
	TA	3	6.7	0	0.0	**	**	0.557 *	3	4.9	0	0.0	**	**	1.000 *
	Variant carrier	26	57.8	9	56.3	0.940	[0.297–2.971]	0.915	35	57.4	13	68.4	1.610	[0.540–4.798]	0.391

TRD: Treatment Resistant Depression. OR: odds ratio.CI: confidence interval. * Fisher exact test. ** One cell count is 0; unable to calculate OR.