Extended Data Fig. 4 ∣. ${\mathit{r}}_{\mathbf{admix}}$ estimation is robust to subsetting PAGE African American individuals based on genotype PCs.

We subsetted PAGE individuals with self-identified race/ethnicity label of ‘African American’ (total N = 17,327) based on genotype PCs and retained N = 17,167 individuals (a). We found that the estimated $r_{\text{admix}}$ were highly consistent between using all PAGE African American individuals (default) and using subset of PAGE African American individuals based on genotype PCs. (b) comparing point estimates of $r_{\text{admix}}$ across 24 traits in PAGE. (Dot on the bottom left of the figure corresponds to MCHC trait, with a small sample size of 3,650.) (c) comparing the meta-analyzed log-likelihood. Results obtained from two sets of individuals are highly consistent.