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. Author manuscript; available in PMC: 2024 May 24.
Published in final edited form as: Nat Genet. 2023 Mar 20;55(4):549–558. doi: 10.1038/s41588-023-01338-6

Extended Data Fig. 3 ∣. radmix estimation is robust to genetic architecture and SNP set.

Extended Data Fig. 3 ∣

We performed radmix estimation under the assumption of alternative genetic architecture and SNP set on real trait analysis across PAGE and UKBB. We compared p-values (for one-sided test of H0:radmix=1) of our default setting (using frequency-dependent genetic architecture and imputed SNPs; Table 1) to those obtained using GCTA genetic architecture and imputed SNPs (a), and to those obtained using frequency-dependent genetic architecture and HM3 SNPs (b). Numerical results are reported in Supplementary Table 8.