Table 4.
Some clinical trials employing metabolomics and proteomics technology in prostate cancer (adopted from clincaltrials.gov, accessed on 22 November 2023).
| Study Title | Aim and Intervention | Country | ID | Status |
|---|---|---|---|---|
| A Multi-omics Study of Metastatic Prostate Cancer (MOSMPCA) | Multi-omics technologies, including proteomic methods, investigating the mechanism underlying tumor progression, identifying distinct subtypes of tumors, and discovering potential treatment targets in patients diagnosed with metastatic prostate cancer. | China | NCT04660617 | Unknown † |
| Decipher Lethal Prostate Cancer Biology—Urine Metabolomics | Developing urine metabolomics markers to improve prostate cancer screening and prevention while reducing the overtreatment of insignificant cases. | Taiwan | NCT03237702 | Recruiting |
| Predictive and Prognostic Markers for Treatment Outcomes in Prostate Cancer Patients | Leveraging urine metabolomics and proteomics profiling to identify predictive and prognostic markers for treatment outcomes in prostate cancer patients. | Taiwan | NCT03237026 | Recruiting |
| UCI 03-72 Prostate Cancer Detection by Serum Proteomic Profiling | Investigators use serum proteomic profiling to assess the predictive capabilities of SELDI (Surface Enhanced Laser Desorption Ionization) analysis compared to PSA tests in determining biopsy outcomes. | California, United States | NCT00355758 | Terminated (lack of personnel) |
| Study in Predicting Outcome of Patients Undergoing Radiation Therapy for Prostate Cancer | A diagnostic trial is underway to investigate blood and urine proteins as potential predictors of treatment outcomes in patients undergoing radiation therapy for prostate cancer. | Maryland, United States | NCT00045331 | Completed |
| Study of Blood and Urine Samples in Patients With Newly Diagnosed Localized Prostate Cancer Treated With Hormone Therapy and Radiation Therapy | In this clinical trial, blood and urine samples from patients with newly diagnosed localized prostate cancer are being studied to explore the impact of hormone therapy and radiation therapy on treatment outcomes using proteomics profiling. | Dublin, Ireland | NCT00955435 | Unknown † |
| Metabolic Impact of Prospective Controlled Mediterranean-Type Diets on Prostate Cancer | To investigate the influence of Mediterranean-type diets on the metabolism of men diagnosed with localized prostate cancer. | Ohio, United States | NCT05590624 | Not yet recruiting |
† Study has passed its completion date, and its status has not been verified in more than two years.