Table 5.

Distribution of allelic frequencies in the PTX3, IL-10, IL-1β, IL-6, and IL-17A SNPs across infected (affected, A; n = 46) and non-infected (unaffected, U; n = 47) patients.

Gene	SNP	A1	F_A	F_U	A2	χ2	p	OR	L95	U95
IL-10	rs3024491	A	32.95	51.09	C	6.06	0.01	0.47	0.26	0.86
	rs1800872	T	38.64	30.43	G	1.34	0.24	1.44	0.78	2.67
IL-1β	rs2853550	A	15.56	4.348	G	6.41	0.01	4.05	1.28	12.83
	rs1143634	A	26.67	21.11	G	0.76	0.38	1.36	0.68	2.71
	rs1143627	G	34.44	25	A	1.94	0.16	1.58	0.83	2.30
PTX3	rs2305619	A	41.49	45.56	G	0.31	0.58	0.85	0.47	1.52
	rs3816527	C	38.30	38.64	A	0.00	0.96	0.99	0.54	1.79
	rs1840680	A	41.49	47.78	G	0.74	0.39	0.78	0.43	1.39
IL-17A	rs2275913	G	32.05	37.5	A	0.52	0.47	0.79	0.41	1.52
IL-6	rs1800797	A	37.21	26.67	G	2.25	0.13	1.63	0.86	3.09
	rs1800796	C	11.11	17.39	G	1.46	0.23	0.59	0.25	1.39

F_A, frequency in affected; F_U, frequency in unaffected; χ², chi-square test; OR, odds ratio; L95 and U95, low and upper 95% confidence interval; p, p-value. Suggestive p-values are in bold (Bonferroni p-value threshold = 0.0045).