Table 6.
Distribution of genotypes in the IL-10 and IL-1β SNPs across infected (affected, A; n = 46) and non-infected (unaffected, U; n = 47) patients.
| Gene | SNP | A1 | A2 | Test | A | U | χ2 | p |
|---|---|---|---|---|---|---|---|---|
| IL-10 | rs3024491 | A | C | GENO | 7/15/22 | 11/25/10 | 7.85 | 0.019 |
| A | C | DOM | 22/22 | 36/10 | 7.84 | 0.0051 | ||
| A | C | REC | 7/37 | 11/35 | 0.90 | 0.34 | ||
| IL-1β | rs2853550 | A | G | GENO | 2/10/33 | 0/4/42 | 5.64 | 0.06 |
| A | G | DOM | 12/33 | 4/42 | 5.07 | 0.024 | ||
| A | G | REC | 2/43 | 0/46 | 2.09 | 0.15 |
A, affected; U, unaffected; χ2, chi-square test; p, p-value. GENO, genotypic test of association in the 2-by-3 table of disease-by-genotype; DOM, genetic test for a dominant model of inheritance of the minor allele; REC, genetic test for a recessive model of inheritance of the minor allele. Suggestive p-values are in bold.