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The effect of a transcription activator-like effector (TALE) binding on the inhibiting effect of chimeric repressor proteins. TALE binding leads to an augmentation of the inhibiting effect of tetracycline repressor (TetR) (A), galactose-responsive transcription factor Gal4 (B), and zinc finger protein (ZFP) Zif268 (C) transcription factors fused with the KRAB repressor domain.
