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(A) Homology between human and mouse CCR5 sequences and sequence of the synthetic peptide. (B) Schematic representation of the FHV capsid protein. The structure displays five different superficial peptide loops (L1, L2, L3, I2, and I3), in each of which a foreign peptide sequence can be inserted and presented on the protein surface in a stable, structurally constrained form. Numbers in parentheses refer to the original amino acid residues replaced by the foreign epitope.
