TABLE 1.

Host cellular molecules acquired by some enveloped viruses

Virusa	Host moleculeb	Function	Incorporated	Reference
EBV	HLA-DR	Antigen presentation	Yes	54
HCMV	CD55	Complement control protein	Yes	101
	CD59	Complement control protein	Yes	101
	Annexin II	Calcium-binding protein	Yes	119
	PPA2, PP1	Serine/threonine protein phosphatase	Yes	2, 68
	β2-microglobulin	β-globulin, MHC-1	Yes	45
VV	α-Tubulin	Cytoskeletal protein	No	26
	HSP70	HSPs, chaperone	No	26
	HSP90	HSPs, chaperone	No	26
	CypA	Immunophilin	Yes	26
	CD46	Complement control protein	Yes	55, 110
	CD55	Complement control protein	Yes	55, 110
	CD59	Complement control protein	Yes	55, 110
	CD29	Integrin β chain	Yes	55, 110
	CD71	Transferrin receptor	Yes	55, 110
	CD81	Tetraspanin	Yes	55, 110
	MHC-1	Antigen presentation	Yes	55, 110
DHBV	p23	Chaperone of HSP90	Yes	52
	HSP90	HSPs, chaperone	Yes	52
VSV	CypA	Immunophilin	Yes	16
MPMV	Tsg101	Vesicular transport protein	Yes	41
	Nedd4	Vesicular transport protein	Yes	41
HTLV-1	Nedd4	Vesicular transport protein	Yes	12
	CD55	Complement control protein	Yes	101
	CD59	Complement control protein	Yes	101
MLV	Actin	Cytoskeletal protein	Yes	73, 114
	α-Tubulin	Cytoskeletal protein	Yes	114
	Clathrin	Vesicular transport protein	Yes	114
	Nucleolin	Nucleolar phosphoprotein	Yes	5
	Ubiquitin	Protein degradation and sorting	Yes	39
	APOBEC3G	Cytosine deaminase	Yes	49
MMLV	CypA	Immunophilin	No	107
	Ubiquitin	Protein degradation and sorting	Yes	78
	Staufen	RNA binding protein	Yes	72
	HSP70	HSPs, chaperone	No	46
HIV-1	CD45	Membrane phosphatase	No	75
	CD46	Complement control protein	Yes	91, 92
	CD55	Complement control protein	Yes	92, 101
	CD59	Complement control protein	Yes	92, 101
	Actin	Cytoskeletal protein	Yes	80, 81
	Pin1	Peptidyl-prolyl isomerase	Yes	80
	tRNA synthetase	Ligase	Yes	47
	GAPDH	Aldehyde oxidoreductases	Yes	78
	MAPK ERK2	Serine/threonine kinase	Yes	25
	HSP27	HSPs, chaperone	No	46
	HSP40	HSPs, chaperone	No	46
	HSP60	HSPs, chaperone	Yes	46
	HSP70	HSPs, chaperone	Yes	46
	HSC70	HSPs, chaperone	Yes	46
	HSP90	HSPs, chaperone	No	46
	CypA	Immunophilin	Yes	37, 107
	CypB	Immunophilin	No	18, 37
	FKBP12	Protein degradation and sorting	Yes	20
	Ubiquitin	Vesicular transport protein	Yes	78
	Tsg101	Vesicular transport protein	Yes	112
	Tal	Vesicular transport protein	Yes	3
	VPS28	Vesicular transport protein	Yes	11, 104, 113
	AIP1/ALIX	Vesicular transport protein	Yes	113
	VPS4B	Vesicular transport protein	Yes	113
	VPS37B	Vesicular transport protein	No	104
	APOBEC3G	Cytosine deaminase	Yes	53, 66, 99
	APOBEC3F	Cytosine deaminase	Yes	58, 115, 123
	UNG	Uracyl-DNA glycosylase	Yes	64, 86, 118
	Staufen	RNA binding protein	Yes	72
	HLA-DR	Antigen presentation	Yes	21-24, 90
	ICAM-1	Adhesion molecule	Yes	35, 36, 67, 82, 89
	Ezrin/myoesin/cofilin	Cytoskeletal proteins	Yes	80, 81
	Thy-1	GP1-anchored protein	Yes	75
	GM1	Ganglioside	Yes	83
	Various other cell surface constituents			76, 109
HIV-2	HSP70	HSPs, chaperone	Yes	46
	CypA	Immunophilin	No	37
	UNG	Uracyl-DNA glycosylase	Yes	86
	Staufen	RNA binding protein	Yes	72
	HLA-DR	Antigen presentation	Yes	4, 76
	MHC-I	Antigen presentation	Yes	4
SIV	CypA	Immunophilin	Yesc	19
	CypB	Immunophilin	Yes	37
	Ubiquitin	Protein degradation and sorting	Yes	79
	AIP1/ALIX	Vesicular transport protein	Yes	113
	APOBEC3G	Cytosine deaminase	Yes	13, 61, 62, 98, 120
	UNG	Uracyl-DNA glycosylase	No	86
Influenza virus	GM1	Ganglioside	Yes	83
Parainfluenza virus	GM1	Ganglioside	Yes	83
HSV	GM1	Ganglioside	Yes	83

^aEBV, Epstein-Barr virus; DHBV, duck hepatitis virus; MPMV, Mason-Pfizer monkey virus; HSV, herpes simplex virus.

^bGAPDH, glyceraldehyde-3-phosphate dehydrogenase; MAPK ERK2, mitogen-activated protein kinase extracellular signal-regulated kinase 2.

^cNot associated with all SIV strains.