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. 2024 May 9;25(10):5160. doi: 10.3390/ijms25105160

Figure 5.

Figure 5

MTX-211 stimulates the ATP hydrolysis activity mediated by ABCG2. The impact of MTX-211 (0–5 µM) on the vanadate (Vi)-sensitive ATPase activity of ABCG2 was evaluated through endpoint Pi release assay. This evaluation was conducted utilizing membrane vesicles obtained from ABCG2 baculovirus-infected High-Five insect cells, following the procedures outlined in Materials and Methods. The data are depicted as mean ± S.D. derived from three independent experiments.