FIG. 5.

MHV-68-specific antibody responses in PKCθ^−/− mice. Serum samples were collected from PKCθ^−/− mice 50 days after infection with MHV-68. Virus-specific antibody responses were determined by ELISA. Data are expressed as mean absorbance values ± standard deviations (error bars) for two separate experiments. Sera from four or five individual mice were tested in each experiment. Asterisks denote that there was a statistically significant difference in antibody titers in PKCθ^−/− and PKCθ^+/+ mice (P < 0.01 [**] and P < 0.001 [***] by Student's t test). Ig (H&L), heavy and light chains of Ig.