Figure 2.

The diagram illustrates HSP60’s engagement in diverse biological functions, depicting various cellular pathways such as mitochondrial integrity, apoptosis, protein folding, inflammatory responses, and disease management. HSP60 plays a pivotal role in maintaining protein homeostasis and thereby ensuring the functionality of crucial processes like development and stress adaptation and maintaining cellular integrity. Moreover, HSP60 influences inflammatory pathways, immune response, and apoptosis in various human diseases, including cancer, aging, cardiomyopathy, arthritis, neurodegeneration, and so on.