Table 2.
In vitro fertilization cycle characteristics.
| Variable | Poor Responders (N = 44) | Normal Responders (N = 342) | High Responders (N = 121) | p-Value |
|---|---|---|---|---|
| Cycle number | 3.34 ± 2.61 | 3.04 ± 2.71 | 2.80 ± 2.27 | 0.488 |
| Protocol (%) | 0.034 | |||
| Agonist | 4 (9.09) | 75 (21.93) | 35 (28.93) | |
| Antagonist | 33 (75) | 186 (54.39) | 56 (46.28) | |
| Other | 7 (15.9) | 81 (23.684) | 30 (24.793) | |
| Daily FSH a dosage | 352.58 ± 142.71 | 249.60 ± 192.04 | 188.07 ± 89.91 | <0.001 |
| Number of gonadotropin stimulation days | 8.34 ± 2.76 | 9.89 ± 2.94 | 10.09 ± 4.05 | 0.003 |
| Total FSH a dosage (IU) | 3028.41 ± 1792.05 | 2375.11 ± 1394.05 | 1869.31 ± 1089.63 | <0.001 |
| Estradiol before triggering (pmol/L) | 2837.32 ± 1592.47 | 5648.49 ± 2954.97 | 7537.29 ± 3615.73 | <0.001 |
| Progesterone before triggering (nmol/L) | 1.43 ± 0.85 | 2.09 ± 2.07 | 2.27 ± 1.43 | <0.001 |
| Endometrial thickness (mm) before triggering | 9.78 ± 2.78 | 10.57 ± 2.32 | 10.57 ± 2.60 | 0.033 |
| Number of oocytes retrieved | 2.41 ± 0.79 | 9.31 ± 3.34 | 20.21 ± 5.40 | <0.001 |
| Fertilization (%) | 0.008 | |||
| IVF b | 15 (34.09) | 80 (23.39) | 19 (15.70) | |
| ICSI c | 28 (63.64) | 205 (59.94) | 79 (65.29) | |
| IVF + ICSI | 0 (0) | 57 (16.67) | 23 (19.01) | |
| Unknown | 1 (2.4) | 0 (0) | 0 (0) | |
| Number of embryos transferred | 1.57 ± 0.62 | 2.09 ± 0.70 | 1.98 ± 0.63 | <0.001 |
| Blastocyst transfer | 0 (0) | 12 (3.51) | 13 (10.74) | 0.002 |
| Number of frozen embryos | 0.07 ± 0.33 | 1.49 ± 1.94 | 4.63 ± 4.09 | <0.001 |
Continuous variables are presented as mean (± SD), and categorical variables are presented as n (%). a FSH—follicle stimulating hormone; b IVF—in vitro fertilization; c ICSI—intracytoplasmic sperm injection. Significant differences (p < 0.004) are presented in bold.