Table 3.
Obstetric and perinatal outcomes.
| Variable | Poor Responders (N = 44) | Normal Responders (N = 342) | High Responders (N = 121) | p-Value |
|---|---|---|---|---|
| Gestational age at delivery (week) | 38.4 ± 1.50 | 38.50 ± 2.06 | 38.64 ± 1.84 | 0.501 |
| Mode of delivery: | 0.036 * | |||
| NVD a (%) | 18 (40.91) | 207 (60.53) | 75 (61.98) | |
| Instrumental delivery b (%) | 8 (18.18) | 33 (9.65) | 18 (14.88) | |
| CD c (%) | 18 (40.91) | 102 (29.82) | 28 (23.14) | |
| Pregnancy-induced hypertension (%) | 1 (2.27) | 3 (0.88) | 2 (1.65) | 0.631 |
| Chronic hypertension (%) | 1 (2.27) | 10 (2.92) | 0 (0) | 0.165 |
| Any hypertension d (%) | 2 (4.55) | 15 (4.39) | 5 (4.13) | 0.992 |
| Mild preeclampsia (%) | 2 (4.55) | 10 (2.92) | 1 (0.83) | 0.321 |
| Severe preeclampsia (%) | 1 (2.27) | 2 (0.58) | 0 (0) | 0.252 |
| Gestational diabetes mellitus (%) | 3 (6.82) | 36 (10.53) | 9 (7.44) | 0.486 |
| Any diabetes mellitus (%) | 2 (4.55) | 37 (10.82) | 10 (8.26) | 0.332 |
| Oligohydramnios (%) | 5 (11.36) | 14 (4.09) | 4 (3.31) | 0.079 |
| Polyhydramnios (%) | 0 (0) | 9 (2.63) | 2 (1.65) | 0.473 |
| 3rd or 4th degree perineal tears (%) | 0 (0) | 3 (0.88) | 0 (0) | 0.482 |
| Post-partum hemorrhage (%) | 0 (0) | 10 (2.92) | 6 (4.96) | 0.244 |
| Blood products transfusion (%) | 0 (0) | 2 (0.58) | 3 (2.48) | 0.150 |
| Maternal fever (%) | 2 (4.55) | 8 (2.34) | 4 (3.31) | 0.658 |
| Shoulder dystocia (%) | 0 (0) | 1 (0.29) | 0 (0) | 0.784 |
| Placental abruption (%) | 1 (2.27) | 6 (1.75) | 0 (0) | 0.32 |
| 5 min Apgar score | 0.506 | |||
| ≤7 (%) | 1 (2.27) | 9 (2.63) | 1 (0.83) | |
| >7 (%) | 43 (97.73) | 332 (97.08) | 119 (98.35) | |
| Not documented (%) | 0 (0) | 1 (0.29) | 1 (0.83) | |
| Birthweight (grams) | 3097.86 ± 505.19 | 3071.30 ± 541.54 | 3116.18 ± 555.52 | 0.823 |
| Birthweight percentile | 52.64 ± 29.01 | 49.31 ± 28.82 | 50.48 ± 27.51 | 0.775 |
| Small-for-gestational-age neonates (%) | 3 (6.82) | 30 (8.77) | 5 (4.13) | 0.250 |
| Large-for-gestational-age neonates (%) | 4 (9.09) | 28 (8.19) | 9 (7.44) | 0.941 |
| Composite outcome e (%) | 13 (29.55) | 111 (32.46) | 29 (23.97) | 0.216 |
Continuous variables are presented as mean (± SD), and categorical variables are presented as n (%). * Overall p-value comparing the 3 study groups. Additionally, no significant differences were found between poor and high responders, normal and high responders, or poor and normal responders (p > 0.002). a NVD—normal vaginal delivery; b instrumental delivery—vacuum extraction or forceps delivery; c CD—cesarean delivery; d any hypertension—including gestational hypertension and chronic hypertension; e composite outcome—any one of the following: preeclampsia (mild or severe), small-for-gestational-age, gestational diabetes, or preterm birth (<37 weeks).