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. 2024 Apr 26;14(5):559. doi: 10.3390/life14050559

Figure 1.

Figure 1

Production, absorption, transport and potential effects of the SCFAs acetate, propionate and butyrate in the human gut. Dietary fibers lead to a higher production of propionate and acetate, while butyrate is primarily obtained through cross-feeding and transformation of other SCFAs. Butyrate, acetate and propionate share some common transporters and are predominantly absorbed through a facilitated process. GPR43 refers to G-protein-coupled-receptors 43, GPR41 to G-protein-coupled-receptors 41, GPR109a refers to G-protein-coupled-receptors 109a, MCT1 to monocarboxylate transporters 1, MCT4 to monocarboxylate transporters 4.