Table 2.
Advantages | Disadvantages | |
---|---|---|
Antibiotics | Immediate effectiveness soon after administration, lifesaving during acute bacterial infections. | Selection of escape mutants, short-term activity, possible side effects. |
Monoclonal Antibodies (mAbs) | Safety, high target-specificity, less susceptible to resistance mechanisms, longer half-lives (~21 days for IgG) compared to antibiotics. | High production cost, possible need for mAb cocktails, problems in reaching the target antigen due to biofilm formation or presence of capsule. |
Vaccines | Multiple antigens can be targeted, low risk of developing resistance, preventive action (prophylaxis), long-lasting effectiveness, induction of immunological memory, herd immunity. | 2–3 weeks required to elicit an immune response, full protection can often require multiple doses. |