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. 2024 Apr 30;11(5):139. doi: 10.3390/jcdd11050139

Table 1.

Clinical data and IL-27 levels in patients with CHD and those without CHD.

All
(n = 402) CHD (−)
(n = 193)
(−) vs. (+) CHD (+)
(n = 209)
Age (years) 67 ± 11 65 ± 12 <0.001 69 ± 10
Sex (men) 276 (69%) 116 (60%) <0.001 160 (77%)
Hypertension 285 (71%) 119 (62%) <0.001 166 (79%)
Hypercholesterolemia 207 (51%) 80 (41%) <0.001 127 (61%)
LDL cholesterol (mg/dL) 114 ± 31 111 ± 29 NS 116 ± 33
HDL cholesterol (mg/dL) 54 ± 15 58 ± 16 <0.001 51 ± 13
Statin 146 (36%) 48 (25%) <0.001 98 (47%)
DM 100 (25%) 26 (13%) <0.001 74 (35%)
Smokers 171 (43%) 68 (35%) <0.01 103 (49%)
LV ejection fraction (%) 63 ± 10 64 ± 9 NS 62 ± 10
CRP levels (mg/L) 0.62 [0.30, 1.53] 0.51 [0.27, 1.24] <0.005 0.80 [0.37, 1.74]
CRP level > 1.0 mg/L 145 (36%) 59 (31%) <0.05 86 (41%)
IL-27 levels (ng/mL) 0.23 [0.15, 0.35] 0.23 [0.14, 0.34] NS 0.23 [0.16, 0.35]
IL-27 level > 0.25 ng/mL 173 (43%) 80 (41%) NS 93 (44%)

The data represent the mean value ± SD or the number (%), except for CRP and IL-27 levels, which represent the median value and interquartile range.