Table 2.
Clinical data and IL-27 levels in patients with cardiovascular events and those with no event.
| All | ||||
|---|---|---|---|---|
| (n = 402) | Event (−) (n = 332) |
(−) vs. (+) | Event (+) (n = 70) |
|
| Age (years) | 67 ± 11 | 66 ± 11 | NS | 69 ± 11 |
| Sex (men) | 276 (69%) | 224 (67%) | NS | 52 (74%) |
| Hypertension | 285 (71%) | 231 (70%) | NS | 54 (77%) |
| Hypercholesterolemia | 207 (51%) | 169 (51%) | NS | 38 (54%) |
| LDL cholesterol (mg/dL) | 114 ± 31 | 112 ± 30 | <0.05 | 121 ± 33 |
| HDL cholesterol (mg/dL) | 54 ± 15 | 55 ± 15 | <0.02 | 50 ± 14 |
| Statin | 146 (36%) | 117 (35%) | NS | 29 (41%) |
| DM | 100 (25%) | 80 (24%) | NS | 20 (29%) |
| Smokers | 171 (43%) | 139 (42%) | NS | 32 (46%) |
| CHD | 209 (52%) | 153 (46%) | <0.001 | 56 (80%) |
| Number of stenotic vessels | 1.0 ± 1.1 | 0.8 ± 1.0 | <0.001 | 1.7 ± 1.1 |
| LV ejection fraction (%) | 63 ± 10 | 63 ± 9 | NS | 62 ± 12 |
| CRP levels (mg/L) | 0.62 [0.30, 1.53] | 0.60 [0.29, 1.50] | NS | 0.85 [0.43, 1.77] |
| CRP level > 1.0 mg/L | 145 (36%) | 114 (34%) | NS | 31 (44%) |
| IL-27 levels (ng/mL) | 0.23 [0.15, 0.35] | 0.22 [0.15, 0.34] | <0.01 | 0.29 [0.19, 0.40] |
| IL-27 level > 0.25 ng/mL | 173 (43%) | 132 (40%) | <0.01 | 41 (59%) |
The data represent the mean value ± SD or the number (%), except for CRP and IL-27 levels, which represent the median value and interquartile range.