The correlation between glycolysis scores or OXPHOS scores with the predicted drug response in mCRPC patients in SU2C/EC clinical studies. (A–C) Correlations between the glycolysis score and the predicted patient response to P276-00, CNF2024, and ivermectin. (D–F) Correlations between the OXPHOS score and the predicted patient response to P276-00, CNF2024, and ivermectin. For each correlation plot, the correlation coefficient and its p-value are given. The statistical analysis was performed by Spearman rank correlation and Student’s t-test with a significance level of α = 0.05. Abbreviations: OXPHOS: oxidative phosphorylation.