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. 2024 Apr 29;17(5):569. doi: 10.3390/ph17050569

Figure 5.

Figure 5

Biomarker discovery for ivermectin. (A) Bar plot about a number of consensual hub genes identified across 12 topological analyses. The red bars indicate the top four-tier consensus genes. (B) Spearman correlation analysis between gene expression and measured area under the drug-response curve (AUC) in pan-cancer CCL. p = 0.05 (dashed red line). The statistical analysis was performed using Spearman rank correlation and Student’s t-test with a significance level of α = 0.05. (C) Survival analysis of patients stratified based on EEF1B2 expression level in the SU2C/EC clinical cohort. The statistical analysis was performed using the log-rank test with a significance level of α = 0.05. Abbreviations: SU2C/EC: Standard Up to Cancer East Coast.