Table 6.
IC50 (µg/mL) of labdanum absolutes and fractions in relation to HepG2 and Caco-2 cell viability at 24 h and 48 h incubation.
| Sample | HepG2 | Caco-2 | ||||
|---|---|---|---|---|---|---|
| 24 h | 48 h | 24 h | 48 h | |||
| Adl | 77.42 ± 3.90 bC | # | 48.27 ± 1.25 aB | 52.84 ± 4.27 aB | # | 36.73 ± 2.00 aA |
| Zam | >200.00 | >200.00 | >200.00 | >200.00 | ||
| Dit | 60.29 ± 2.27 aB | 53.77 ± 4.08 aB | 44.58 ± 4.51 aA | 38.67 ± 2.01 aA | ||
| Flv | 76.73 ± 2.97 bC | # | 52.84 ± 1.23 aA | 69.50 ± 2.11 bB | # | 48.30 ± 2.67 bA |
Value presented as mean ± standard deviation (n = 3). Dit and Flv are fractions of Adl absolute. Different coefficient small or capital letters mean statistical differences between mean values within each column or row, respectively, by the post hoc Tuckey’s test (α = 0.05). # means statistical differences between incubation times by the post hoc Tukey’s test (α = 0.05).