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. 2024 May 7;29(10):2176. doi: 10.3390/molecules29102176

Scheme 8.

Scheme 8

Proposed mechanism for the construction of 3-hydroxyalkyl isoquinolone 6b from alkyne-tethered hydroxamic ester 6a via Rh(III)-catalyzed intramolecular C-H activation and annulation. Created by us and based on the original work.