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. 2024 May 7;29(10):2176. doi: 10.3390/molecules29102176

Scheme 16.

Scheme 16

Proposed mechanism for the construction of isoindolo [2,1-b]isoquinolin-5(7H)-one 10c from N-(pivaloyloxy)benzamide 10a and 2-alkynyl aldehyde 10b via Rh(III)-catalyzed intermolecular C-H activation and annulation. Created by us and based on the original work.