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. 2024 May 7;29(10):2176. doi: 10.3390/molecules29102176

Scheme 17.

Scheme 17

Proposed mechanism for the construction of isoindolo [2,1-b]isoquinolin-5(7H)-one 10g from alkyne-tethered hydroxamic ester 10f via Rh(III)-catalyzed sequential C(sp2)-H activation and C(sp3)-H amination. Created by us based on the original work.