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SGx altered serum BA composition in both (A) WT and (B) Fgf15 ile−/− mice. BA composition was determined by HPLC/MS in both WT and Fgf15 ile−/− mice at preop state, and 1, 2, and 3 months following SGx (n=4, 4, 6, 4 for WT, respectively; n=5, 6, 6, 8 for Fgf15 ile−/−, respectively). Abbreviations: BA, bile acid; SGx, vertical sleeve gastrectomy; WT, wild type.
