Table 1.
Clinical applications of SDT for the treatment of tumors.
| Sonosensitizers | Cancer Type | Treatments | Result | Refs. |
|---|---|---|---|---|
| Ce6 | breast cancer | macrophage-activating factor + SDT + hormone therapy | Complete resolution of pleural effusion and intrapleural nodular tumors without serious adverse effects | [124] |
| Two new chlorophyll derivatives | breast cancer | SDT + PDT | Almost no toxicity, and may dramatically enhance chemo efficacy in some refractory advanced breast cancer cases | [129] |
| Sonoflora 1™ | breast cancer | SDT | Patients with advanced cancer were treated safely and effectively | [130] |
| Sonoflora 1™ | breast cancer | SDT + PDT | All patients had significant partial or complete responses | [123] |
| 5-aminolevulinic acid | Diffuse intrinsic pontine glioma | SDT | Cohort 1 was completed without dose-limiting toxicity | [131] |