Table 2. Changes in body weight treated with S. heteromalla CME for seven days.
| (A) Body Weight (Mean ± SEM) (Treated with S. heteromalla) | |||||
| Dose (mg/kg) b.w | Group-I (Control) |
Group-II (500 mg) |
Group-III (1000 mg) |
Group-IV (2000 mg) |
Group-V (3000 mg) |
| Weight (g) before drug | 31.4 ± 0.25 | 31.30 ± 0.25 | 31.7± 0.28 | 31.2 ± 0.25 | 31.8 ± 0.17 |
| Weight (g) after drug | 31.6 ± 0.010 | 31.8 ± 0.010 | 31.2 ± 0.010 | 26.58± 0.023 | 25.7 ± 0.011 |
| (B) Dose Vs mortality and LD50 value of S. heteromalla CME | |||||
| Dose (mg/kg) b.w | Group-I Normal saline |
Group-II (500 mg) |
Group-III (1000 mg) |
Group-IV (2000 mg) |
Group-V (3000 mg) |
| No of animals | 6 | 6 | 6 | 6 | 6 |
| Death /Mortality | 0 | 0 | 0 | 6 | 6 |
| LD50 = 1500 mg/kg | |||||
| ED50(max) = 1000 mg/kg | |||||
p <0.05 (S), Values are expressed as ± SEM (standard error of mean), S = significant. B.w: body weight.