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. 2024 May 24;19(5):e0302657. doi: 10.1371/journal.pone.0302657

Table 7. Accelerated stability study at 40°C ± 2°C / 75% RH ± 5% RH for six months.

Parameters	Months
Parameters	Initial	1^st	2^nd	3^rd	4^th	5^th	6^th
Physical appearance	Brownish green	Brownish green	Brownish green	Brownish green	Brownish green	Brownish green	Brownish green
Hardness	6.2 ± 0.05	6.2 ± 0.05	6.2 ± 0.05	6.2 ± 0.05	6.7 ± 0.05	7.0 ± 0.05	7.1 ± 0.05
Friability	0.36 ±0.14	0.36 ±0.14	0.36 ±0.14	0.36 ±0.14	0.36 ±0.14	0.36 ±0.14	0.36 ±0.14
Disintegration time	8.4± 0.11	8.4± 0.11	8.6± 0.12	8.9± 0.11	8.6± 0.12	8.8± 0.13	9 ± 0.10
Drug release	87.48	87.22	87.02	86.71	86.53	86.03	85.89