Figure 1.

Clinical signs of diseased Chinese tongue soles. (A-1,A-2) Anatomical symptoms including a swollen kidney and spleen filled with white nodules, and punctate hemorrhages on the liver; (B) statistics on daily and cumulative mortality; (C-1) diseased fish liver showing oedematous (black arrow) and necrotic (red arrow) hepatocytes; (C-2) diseased fish spleen showing different levels of vacuolation (blue arrow) and necrosis (green arrow); (C-3) renal tubular atrophy and necrosis (yellow arrow), and sparsely arranged lymphocytes (orange arrow) in a diseased fish kidney.