Table 2.
Toxicokinetic characteristics of OTA after a single oral bolus administration of DON, OTA, and AFB1 whether or not combined with the algoclay-based decontaminant.
| Toxicokinetic Parameter | Mycotoxins | Mycotoxins + Algoclay-Based Decontaminant |
p-Value | SEM |
|---|---|---|---|---|
| AUC0–24h (h.ng/mL) | 205.99 b | 114.74 a | <0.001 | 18.48 |
| Cmax (ng/mL) | 31.45 | 26.48 | 0.37 | 5.38 |
| Tmax (h) | 3.28 | 1.75 | 0.31 | 1.45 |
| Relative F (%) | 100 | 55.7 |
a,b Values without a common letter within a row differ significantly (p < 0.05). SEM: standard error of the mean; AUC: area under the curve; Cmax: maximal plasma concentration; Tmax: time at maximal plasma concentration; Relative F: relative oral bioavailability. The experiment was carried out with eight repetitions, where each repetition represents one broiler chicken.