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. 2024 May 5;12(5):500. doi: 10.3390/vaccines12050500

Table 6.

Summary of risk ratio (RR) for main outcomes from collected studies by age groups of participants (note: 95% CI = 95% confidence interval; ARI = acute respiratory illness; LRTD = lower respiratory tract disease).

Outcome Studies Subjects Aged ≥70/75 Years
(/Total, %)
Subjects Aged
<70/75 Years
(/Total, %)
RR (95% CI) Heterogeneity
I2 (95% CI) τ2 (95% CI) Q (p-Value)
First Season
ARI [51,52,82] 18/13,627 (0.13%) 43/23,951 (0.18%) 0.800
(0.459; 1.392)
0.0%
(0.0; 89.6)
0.000
(0.000; 6.721)
1.40 (0.496)
LRTD
(2 symptoms)
[51,52,82] 6/13,627 (0.04%) 24/23,951 (0.10%) 0.522
(0.211; 1.291)
0.0%
(0.0; 89.6)
0.000
(0.000; 14.509)
0.84 (0.657)
LRTD
(3+ symptoms)
[51,52,81,82] 5/19,130 (0.03%) 13/30,914 (0.04%) 0.819
(0.304; 2.207)
0.0%
(0.0; 84.7)
0.000
(0.000; 7.504)
1.30 (0.729)