Table 1. p53, c-erbB-2 and epidermal growth factor receptor (EGFR) expression in head and neck squamous cell carcinomas (SCC) and corresponding mucosa (paired).
| Mucosa | Head and neck SCC | |||
|---|---|---|---|---|
| p53- n (%) | p53+ n (%) | Total n (%) | ||
| p53 - | 16 (50.0) | 4 (12.5) | 20 (62.5) | |
| p53 + | 1 (3.1) | 11 (34.4) | 12 (37.5) | |
| N/A | 7 | 15 | 22 | |
| Total | 24 | 30 | 54 | |
| c-erbB-2-n (%) | c-erbB-2+n (%) | Total n (%) | ||
| c-erbB-2 - | 12 (36.4) | 1 (3.0) | 13 (39.4) | |
| c-erbB-2 + | 12 (36.4) | 8 (24.2) | 20 (60.6) | |
| N/A | 9 | 12 | 21 | |
| Total | 33 | 21 | 54 | |
| EGFR-n (%) | EGFR+n (%) | N/A | Total n (%) | |
| EGFR - | 8 (26.7) | 7 (23.3) | 0 | 15 |
| EGFR + | 4 (13.3) | 11 (36.7) | 1 | 16 |
| N/A | 8 | 15 | 0 | 23 |
| Total | 20 | 33 | 1 | 54 |
p53- = p53 not detected; p53+ = p53 detected; c-erbB-2- = c-erbB-2 not detected; c-erbB-2 + = c-erbB-2 detected; EGFR- = EGFR not detected; EGFR+ = EGFR detected. N/A = not applicable, considering that 22 patients had no evaluation of p53 in mucosa to compare with the corresponding SCC; 21 patients had no evaluation of c-erbB-2 in mucosa to compare with the corresponding SCC; 23 patients had no evaluation of EGFR in mucosa to compare with the corresponding SCC; and one patient had no evaluation of EGFR in SCC to compare with the corresponding mucosa.