Table 2.
Inhibition of HSV by algal polysaccharide extract from Cladophora spp. upon treatment before, during and after viral adsorption with and without removal the algal extract from the infected Vero cells.
| Inhibition mechanisms | HSV-1 | HSV-2 | |
|---|---|---|---|
| Before viral adsorption | EC50 (µg mL−1) | 70.31 | 5.85 |
| Selective Index (SI)* | > 71.11 | > 854.70 | |
| During viral adsorption | EC50 (µg mL−1) | 15.17 | 2.57 |
| Selective Index (SI) * | > 329.60 | > 1945.52 | |
| After viral adsorption with removal of the algal extract | EC50 (µg mL−1) | > 5000 | > 5000 |
| Selective Index (SI)* | 1 | 1 | |
| After viral adsorption without removal of the algal extract | EC50 (µg mL−1) | 9.78 | 26.96 |
| Selective Index (SI) * | > 511.25 | > 185.46 | |
*Selective Index (SI) = 50% Cytotoxic dose (CD50)/50% Effective dose (ED50).