Menon, 2019; Jiang et al., 2017; Ma et al., 2023; Huang et la., 2020; Huang et al., 2022; van Ommen et al., 2022; Xiang et al., 2019; Kandilarova et al., 2021; Hummer et al., 2020; Sarpal et al., 2022
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Disconnectivity between Salience Network, Central Executive Network and Default Mode Network is related to cognitive impairments in schizophrenia. Connectivity within SN, CEN and DMN networks is usually increased, however the connections between them are decreased. |
N/A |
van Ommen et al., 2022; Kandilarova et al., 2021; Xi et al., 2021; Rodriguez et al., 2019; Xu et al., 2019; Hare, 2021; Hare et al., 2019
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Triple network disconnectivity and aberrant patterns between and within networks are associated with schizophrenia negative and positive symptoms. |
N/A |
McCutcheon et al, 2020; Huang et al., 2022; Conio et al., 2020; Han et al., 2020; Fan et al., 2021; Maximo et al., 2021
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Mesolimbic dopamine system, serotonergic pathways, glutamatergic metabolism and GABA may modulate functional disconnectivities and that are associated with particular schizophrenia symptoms. |
Neurotransmitter Theory |
McCutcheon et al, 2020
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The interplay of psychosocial and psychological stressors, coupled with dopamine dysfunction in subcortical regions, may significantly contribute to the emergence of positive symptoms in schizophrenia. |
Vulnerability/Stress Model |