Table 2.
Odds of Developing CKD stage 3a or Higher Based on Race and APOL1 Status
| 25 Years (Only Those Who Are Alive) |
30 Years (Only Those Who Are Alive) |
|||||||
|---|---|---|---|---|---|---|---|---|
| At risk | Events, N (%) | UnadjustedOR (95% CI), P Value | Adjusteda OR (95% CI), P value | At Risk | Events, N (%) | Unadjusted OR (95% CI), P Value | Adjusteda OR (95% CI), P Value | |
| Black high-risk | 45 | 15 (33%) | REF | REF | 35 | 15 (43%) | REF | REF |
| Black low-risk | 319 | 81 (25%) | 0.7 (0.4-1.3), 0.3 | 0.7 (0.4-1.5), 0.4 | 212 | 77 (36%) | 0.8 (0.4-1.5), 0.5 | 0.9 (0.4-2), 0.9 |
| White | 2,610 | 779 (30%) | 0.9 (0.5-1.6), 0.6 | 1.04 (0.5-2), 0.9 | 1,617 | 642 (40%) | 0.9 (0.5-1.7), 0.7 | 1.3 (0.6-2.9), 0.5 |
CKD stage 3a or worse is defined as eGFRcr-cys ≤ 60 mL/min/1.73 m2.
Abbreviations: CI, confidence interval; OR, odds ratio; REF, reference.
a
Adjusted for eGFRcr, age, systolic and diastolic blood pressure, BMI, sex, employment status, education, smoking status, follow-up with primary care, family history of diabetes and hypertension.