Figure 7.

Changes in Sirt1 and CD38 protein expression and assessment of the degree of deacetylation of downstream molecules in the ONC model. (A) The expression of Sirt1 protein in retina was detected by WB in the sham operation group and crush on day 3, day 7, and day 14. (B) The expression of CD38 protein in retina was detected by WB in the sham operation group and crush on day 3, day 7, and day 14. (C) The expression of Ac-p53 protein in retina was detected by WB in the sham operation group and crush on day 3, day 7, and day 14. (D) The expression of Ac-p65 protein in retina was detected by WB in the sham operation group and crush on day 3, day 7, and day 14. (E) The expression of IL-1β protein in retina was detected by WB in the sham operation group and crush on day 3, day 7, and day 14. (F) The expression of Caspase3 protein in retina was detected by WB in the sham operation group and crush on day 3, day 7, and day 14. WT, wild type; KO, knockout; data presented as: mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001.