Table 1.
C-CD (n = 11) | SB-CD (n = 8) | P value | |
---|---|---|---|
Mean age at diagnosis, y | 10.9 | 11 | .95 |
Sex, % female | 36.3 | 25 | 1 |
Ethnicity, % Caucasian | 72.7 | 87.5 | .6 |
Paris location, % | |||
L1 | 0 | 50 | .018 |
L2 | 54.5 | 0 | .018 |
L3 | 45.5 | 25 | .63 |
L4a | 18.2 | 37.5 | .6 |
L4b | 0 | 100 | .0001 |
Paris behavior, % | |||
B1 | 45.5 | 12.5 | .177 |
B2 | 27.2 | 62.5 | .18 |
B3 | 18.2 | 0 | .485 |
B2/B3 | 9.1 | 25 | .546 |
Perianal disease, % yes | 36.4 | 12.5 | .338 |
Presence of granulomas, % yes | 33.3 (2/6) | 33.3 (3/9) | 1 |
Surgical intervention required, % yes | 54.5 | 75 | .633 |
Surgery in first 2 years, % yes | 33.3 (2/6) | 50 (3/6) | 1 |
Type of surgery, % | n = 6 | n = 6 | |
Partial colectomy | 50 | 50 | 1 |
Total colectomy | 33.3 | 0 | .455 |
Ileocecotomy | 0 | 16.7 | 1 |
Enterectomy | 16.7 | 66.7 | .242 |
Small-bowel diversion only | 16.7 | 0 | 1 |
Biologic agents used before surgery, % | n = 6 | n = 6 | |
Infliximab | 100 | 66.7 | .455 |
Adalimumab | 83.3 | 33.3 | .242 |
Ustekinumab | 16.7 | 16.7 | 1 |
Vedolizumab | 16.7 | 0 | 1 |
Biologic agents used in nonsurgical patients, % | n = 5 | n = 2 | |
Infliximab | 80 | 100 | .49 |
Adalimumab | 60 | 0 | .429 |
C-CD, colon-predominant Crohn’s disease; SB-CD, small-bowel–predominant Crohn’s disease.