Table 2.
Clinical characteristics of maternal-neonatal listeriosis
| Maternal case 1 | Neonatal case 1 | Maternal case 2 | Neonatal case 2 | Maternal case 3 | Neonatal case 3 | Maternal case 4 | Neonatal case 4 | Maternal case 5 | Neonatal case 5 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Age | 32 years | 1 day | 31 years | 1 day | 31 years | 1 day | 30 years | 1 day | 29 years | 1 day |
| Sex | Female | Female | Female | Male | Female | Female | Female | Female | Female | Female |
| Gestation | 31 weeks | 35 weeks | 34 weeks | 30 weeks | 38 weeks | |||||
| Type of listeriosis | Bacteremia | Bacteremia | Bacteremia | Bacteremia | Bacteremia | Bacteremia | Bacteremia | Neurolisteriosis | Bacteremia | Bacteremia |
| Presentation | Fever | Fetal distress, sepsis | Decreased fetal movement | Fetal distress, septic shock, neonatal necrotizing enterocolitis, intubation | Fever, abdominal pain | Fetal distress, sepsis | Fever, cough | Fetal distress, respiratory failure, septic shock, diffuse intravascular coagulation, cerebral edema, intubation | Abdominal pain | Fetal distress, sepsis, respiratory failure |
| WBC (× 109/l) | 15.56 | 1.88 | 16.76 | 12.12 | 24.05 | 9.49 | 19.23 | 4.08 | 22.84 | 16.53 |
| Platelet (× 109/l) | 154 | 87 | 214 | 154 | 216 | 128 | 182 | 83 | 175 | 114 |
| RBC (× 1012/l) | 3.35 | 4.07 | 3.30 | 3.78 | 4.33 | 4.04 | 4.13 | 3.88 | 4.64 | 4.42 |
| Hemoglobin (g/l) | 106 | 172 | 98 | 138 | 109 | 151 | 116 | 151 | 130 | 167 |
| CRP (mg/l) | 194 | 40 | 128 | 41.62 | 59 | 32 | 18 | 51 | 135 | 28.16 |
| Procalcitonin (μg/l) | 1.01 | < 0.05 | 3.68 | 23.12 | 0.23 | 19.52 | < 0.05 | 35 | 0.49 | 37.58 |
| Culture sites | Placenta | Blood, laryngeal swab | Placenta | Blood, cochlear swab | Placenta | Blood, cochlear swab | Blood | Blood, cochlear swab, tracheal tube tip | Placenta | Blood, laryngeal swab |
| Antibiotic | Piperacillin/tazobactam | Meropenem | Piperacillin/tazobactam | Piperacillin/tazobactam | Penicillin | Penicillin | Penicillin | Penicillin | Penicillin | Meropenem + penicillin |
| Outcome | Recovered | Survived | Recovered | Decreased on day 3 | Recovered | Survived | Recovered | Decreased on day 6 | Recovered | Decreased on day 2 |
WBC white blood cells, RBC red blood cells, CRP C-reactive protein